TAY-SACHSDISEASEJOHNR

Tay - Sachs disease **Description:** Tay – Sachs is a disease occurs when the body becomes lack of hexosaminidase A (hex A is a protein to help break down a chemical found in nerve tissue that is called gangliosides.) This disease is caused by a defective gene on chromosome.

**Inheritance: **  Tay – Sachs is inherited by parents. If both of them carry the defective genes, a child has 25% of getting chance of developing the disease. Anyone can be carrier of this disease but it is common among Ashkenazi Jewish population.

**Symptoms: ** There are many symptoms · Blindness · Deafness · Loss of muscle strength · Slow growth · Seizures · Loss of brain function

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**Diagnosis: **  You need to do a special blood test to find out if you have Tay – Sachs. Just one simple blood test could tell DNA codes. **Treatment: ** There is no cure for Tay – Sachs, but there is way to slow down and there is way to control the symptoms.

**<span style="color: black; font-family: Times,serif; font-size: 12pt;">Research: ** <span style="color: black; font-family: Times,serif; font-size: 12pt; line-height: normal; margin-bottom: 0in;">They are focusing on trying to change lifestyle and trying to deal with the symptoms.

**<span style="color: black; font-family: Times,serif; font-size: 12pt;">Additional Facts: ** · **<span style="color: black; font-family: Times,serif; font-size: 12pt;">Tay – Sachs is a Jewish genetic disease ** · **<span style="color: black; font-family: Times,serif; font-size: 12pt;">Babies who are born with this disease usually dies by age 4 **

**<span style="color: black; font-family: Times,serif; font-size: 12pt;">Punnett Square: **

**<span style="color: black; font-family: Times,serif; font-size: 12pt;">Pedigree Chart: Keys: ** **<span style="color: black; font-family: Times,serif; font-size: 12pt;">P: Dominant p: Recessive **

**<span style="color: black; font-family: 'Times New Roman',serif;">﻿ ****<span style="color: black; font-family: Times,serif; font-size: 12pt;">Resources: **<span style="color: black; font-family: Times,serif; font-size: 12pt;"> www.Ncbi.nlm.nih.gov/pubmedhealth/pmh00023901 <span style="color: black; font-family: Times,serif; font-size: 12pt; line-height: 14.25pt; margin-bottom: 0in;"> www.Jewishfederaction.org/page.asnx?=30796 <span style="color: black; font-family: Times,serif; font-size: 12pt; line-height: 14.25pt; margin-bottom: 0in;"> www.disabled-world.com/disability/types/tay-sachs.php