Sickle+cell+disease-Shannon+H

Sickle cell anemia is an inherited blood disorder characterized primarily by chronic anemia and periodic episodes of pain. The problem involves hemoglobin, a component of red blood cells. Hemoglobin molecules in each red blood cell carry oxygen from the lungs to body organs and tissues and bring carbon dioxide back to the lungs.
 * Description: **

**Inheritance: **If one parent has Sickle Cell anemia (SS) and the other has Sickle Cell trait (AS) there is a fifty percent chance of a child having Sickle Cell disease, and a fifty percent chance at having Sickle Cell trait. When both parents have Sickle Cell trait, there is a twenty-five percent chance if the child having Sickle Cell disease.

**Symptoms **: General Symptoms in Infants. In infants, symptoms do not usually appear until late in the baby's first year. Most commonly, they include:

•Fever •Swelling of the hands and feet •Pain in the chest, abdomen, limbs, and joints •Nosebleeds and frequent upper respiratory infections

General Symptoms in Children. Pain is the most common complaint. It can be acute and severe or chronic, usually from orthopedic problems in the legs and low back. Other symptoms include:

•Fatigue and shortness of breath (signs of anemia) •Irritability •yellowish discoloration of the skin and eyes

Additional Symptoms in Adolescence or Adulthood. Symptoms of childhood continue in adolescence and adulthood. In addition, patients may experience:

•Delayed puberty (in young teenagers) <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 14.25pt; margin: 0in 0in 0pt;">•Severe joint pain <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 14.25pt; margin: 0in 0in 0pt;">•Progressive anemia <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 14.25pt; margin: 0in 0in 0pt;">•Leg sores <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 14.25pt; margin: 0in 0in 0pt;">•Gum disease <span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">•Vision problems

**<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Daily Life: media type="custom" key="9499882" **

**<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Diagnosis: **<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">In all states across the country, it is mandated that each child born, with have just a simple blood test to determine if they have Sickle Cell disease.

**<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Treatment: **<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Some treatments can relive symptoms like, pain, prevent infections, prevent organ damage and strokes. Though, blood and marrow transplants may offer a cure for a small number of people who have Sickle Cell disease.

**<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Research: ** <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 115%;">When you have Sickle Cell disease, it is easy to get infections. To help prevent infections, doctors have found different shots to help prevent infections. Also make sure you have good hygiene. (wash and sanitize your hands often.) <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 0px; overflow: hidden;"> <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 115%;">
 * <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 115%;">Punnett Square: **
 * <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 0px; overflow: hidden;">﻿ **
 * <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 115%;">Pedigree Chart: **