Progeria+-+Ryan+M.

| Progeria | **Description: ** Progeria is a disease that causes rapid aging starting in childhood. It is a rare disease that resembles normal human aging but at a much faster rate. The average age of death for victims with Progeria is 13-years old, usually do to a heart attack or stroke.

**Gene Mutation: ** Most children with Progeria have a mutation on the gene that encodes the protein lamin “A”. Lamin “A” is located on one of the 22 pairs of non-sex chromosomes in the cell nucleus. Essentially what this mutation does is it makes the lamin “A” longer than lamin “C” and these proteins are used to create the Nuclear Envelope. The defective Nuclear Envelope causes the Nucleus to become unstable. The reaction of this is known as Progeria.

**Symptoms: ** Since Progeria resembles normal human aging, most of the symptoms are similar to that of an elderly person. Some symptoms are: · Loss of eyebrows/eyelashes · Baldness · Limited range of motion and strength · Narrow, wrinkled face · Short stature · Larger head compared to their face

**Daily Life: ** media type="custom" key="9500140"

**Diagnosis: ** <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: 14.25pt; margin: 0in 0in 0pt;">None

**<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Treatment: ** <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: normal; margin: 0in 0in 0pt;">There is no current Treatment for Progeria

**<span style="color: black; font-family: 'Times','serif'; font-size: 12pt;">Research: ** <span style="color: black; font-family: 'Times','serif'; font-size: 12pt; line-height: normal; margin: 0in 0in 0pt;">Progeria Research Foundation, Inc. – //progeriaresearch.org//